Members

Andreas Schueller

Associate Professor

Group Leader

Phone Office

+56 2 2354 1842

Phone Lab

+56 2 2354 2605

Contact

aschueller@bio.puc.cl

Tomás Cáceres Madariaga

Biochemistry Undergraduate student

Working on ...

Undergraduate thesis: "In silico characterization of auxin binding specificity/affinity to receptors of the TIR1/AFB1-5 family."

Contact

caceres.tomas@uc.cl

Joaquín Gutiérrez Benavente

PhD(c)/MSc Molecular Genetics and Microbiology

Working on ...

Peptide design for enzyme inhibition.

Contact

jmgutierrez4@uc.cl

Miguel Antonio Sáez Ortega

Biochemistry Undergraduate student

Working on ...

Thesis in the de novo target prediction

Contact

masaez4@uc.cl

Andrés Patricio Ibacache Chía

PhD student in Molecular Genetics and Microbiology.

Working on ...

In silico identification of inhibitory molecules of monocarboxylate transporters and their validation as targets for the inhibition of tumor cell proliferation.

Contact

aaibacache@uc.cl

Hade Ramos Acevedo

Biochemist, PhD student in Molecular Genetics and Microbiology

Working on ...

Contact

haramos@uc.cl

Fabian Melo Montenegro

Biology Undergraduate student

Working on ...

Contact

fnmelo@uc.cl

Former Members

Carlos Vigil Vásquez

Biochemistry

Contact

carlos.vigil.v@gmail.com

Daniela Herrera

PhDc Engineering sciences

Contact

dpherrer@uc.cl

Mauricio Ruiz

Bioinformatic engineer

Contact

ruiz.moraga.90@gmail.com

Claudio Ponce Acosta

Biochemistry

Contact

caponce@uc.cl

unlink(): Argument #1 ($filename) must not contain any null bytes (500 Internal Server Error)

Symfony Exception

Symfony Docs

ValueError

HTTP 500 Internal Server Error

unlink(): Argument #1 ($filename) must not contain any null bytes

Exception

ValueError

in vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php (line 351)
  2.             if ($csvTime >= $minimalProfileTimestamp) {
  3.                 break;
  4.             }
  6.             @unlink($this->getFilename($csvToken));
  7.             $offset += \strlen($line);
  8.         }
  9.         fclose($handle);
  11.         file_put_contents($file.'.offset', $offset);
in vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php unlink (line 351)
  2.             if ($csvTime >= $minimalProfileTimestamp) {
  3.                 break;
  4.             }
  6.             @unlink($this->getFilename($csvToken));
  7.             $offset += \strlen($line);
  8.         }
  9.         fclose($handle);
  11.         file_put_contents($file.'.offset', $offset);
in vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php -> removeExpiredProfiles (line 200)
  1.                 $profile->getVirtualType() ?? 'request',
  2.             ]);
  3.             fclose($file);
  5.             if (1 === mt_rand(1, 10)) {
  6.                 $this->removeExpiredProfiles();
  7.             }
  8.         }
  10.         return true;
  11.     }
in vendor/symfony/http-kernel/Profiler/Profiler.php -> write (line 104)
  1.             if ($collector instanceof LateDataCollectorInterface) {
  2.                 $collector->lateCollect();
  3.             }
  4.         }
  6.         if (!($ret = $this->storage->write($profile)) && null !== $this->logger) {
  7.             $this->logger->warning('Unable to store the profiler information.', ['configured_storage' => $this->storage::class]);
  8.         }
  10.         return $ret;
  11.     }
in vendor/symfony/http-kernel/EventListener/ProfilerListener.php -> saveProfile (line 135)
  1.             }
  2.         }
  4.         // save profiles
  5.         foreach ($this->profiles as $request) {
  6.             $this->profiler->saveProfile($this->profiles[$request]);
  7.         }
  9.         $this->profiles = new \SplObjectStorage();
  10.         $this->parents = new \SplObjectStorage();
  11.     }
in vendor/symfony/event-dispatcher/Debug/WrappedListener.php -> onKernelTerminate (line 116)
  1.         $this->priority ??= $dispatcher->getListenerPriority($eventName, $this->listener);
  3.         $e = $this->stopwatch->start($this->name, 'event_listener');
  5.         try {
  6.             ($this->optimizedListener ?? $this->listener)($event, $eventName, $dispatcher);
  7.         } finally {
  8.             if ($e->isStarted()) {
  9.                 $e->stop();
  10.             }
  11.         }
in vendor/symfony/event-dispatcher/EventDispatcher.php -> __invoke (line 220)
  2.         foreach ($listeners as $listener) {
  3.             if ($stoppable && $event->isPropagationStopped()) {
  4.                 break;
  5.             }
  6.             $listener($event, $eventName, $this);
  7.         }
  8.     }
  10.     /**
  11.      * Sorts the internal list of listeners for the given event by priority.
in vendor/symfony/event-dispatcher/EventDispatcher.php -> callListeners (line 56)
  1.         } else {
  2.             $listeners = $this->getListeners($eventName);
  3.         }
  5.         if ($listeners) {
  6.             $this->callListeners($listeners, $eventName, $event);
  7.         }
  9.         return $event;
  10.     }
in vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php -> dispatch (line 139)
  1.         try {
  2.             $this->beforeDispatch($eventName, $event);
  3.             try {
  4.                 $e = $this->stopwatch->start($eventName, 'section');
  5.                 try {
  6.                     $this->dispatcher->dispatch($event, $eventName);
  7.                 } finally {
  8.                     if ($e->isStarted()) {
  9.                         $e->stop();
  10.                     }
  11.                 }
in vendor/symfony/http-kernel/HttpKernel.php -> dispatch (line 115)
  1.     /**
  2.      * @return void
  3.      */
  4.     public function terminate(Request $request, Response $response)
  5.     {
  6.         $this->dispatcher->dispatch(new TerminateEvent($this, $request, $response), KernelEvents::TERMINATE);
  7.     }
  9.     /**
  10.      * @internal
  11.      */
in vendor/symfony/http-kernel/Kernel.php -> terminate (line 157)
  1.         if (false === $this->booted) {
  2.             return;
  3.         }
  5.         if ($this->getHttpKernel() instanceof TerminableInterface) {
  6.             $this->getHttpKernel()->terminate($request, $response);
  7.         }
  8.     }
  10.     /**
  11.      * @return void
in vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php -> terminate (line 53)
  1.         } else {
  2.             $response->send();
  3.         }
  5.         if ($this->kernel instanceof TerminableInterface) {
  6.             $this->kernel->terminate($this->request, $response);
  7.         }
  9.         return 0;
  10.     }
  11. }
in vendor/autoload_runtime.php -> run (line 29)
  1. $app = $app(...$args);
  3. exit(
  4.     $runtime
  5.         ->getRunner($app)
  6.         ->run()
  7. );
require_once('/var/www/schuellerlab.org/vendor/autoload_runtime.php') in public/index.php (line 5)
  1. <?php
  3. use App\Kernel;
  5. require_once dirname(__DIR__).'/vendor/autoload_runtime.php';
  7. return function (array $context) {
  8.     return new Kernel($context['APP_ENV'], (bool) $context['APP_DEBUG']);
  9. };

Logs 2

Level Channel Message
INFO 01:05:57 request Matched route "ldm_members". 
{
    "route": "ldm_members",
    "route_parameters": {
        "_route": "ldm_members",
        "_controller": "App\\Controller\\DefaultController::membersAction"
    },
    "request_uri": "http://dna.bio.puc.cl/members",
    "method": "GET"
}
DEBUG 01:05:57 security Checking for authenticator support. 
{
    "firewall_name": "main",
    "authenticators": 0
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\DebugHandlersListener::configure". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\DebugHandlersListener::configure"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\ValidateRequestListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ValidateRequestListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\SessionListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\SessionListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleListener::setDefaultLocale". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleListener::setDefaultLocale"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\RouterListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\RouterListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleAwareListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleAwareListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Bundle\SecurityBundle\Debug\TraceableFirewallListener::configureLogoutUrlGenerator". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Bundle\\SecurityBundle\\Debug\\TraceableFirewallListener::configureLogoutUrlGenerator"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Bundle\SecurityBundle\Debug\TraceableFirewallListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Bundle\\SecurityBundle\\Debug\\TraceableFirewallListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Knp\Bundle\PaginatorBundle\Subscriber\SlidingPaginationSubscriber::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Knp\\Bundle\\PaginatorBundle\\Subscriber\\SlidingPaginationSubscriber::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.controller" to listener "Symfony\Bundle\FrameworkBundle\DataCollector\RouterDataCollector::onKernelController". 
{
    "event": "kernel.controller",
    "listener": "Symfony\\Bundle\\FrameworkBundle\\DataCollector\\RouterDataCollector::onKernelController"
}
DEBUG 01:05:57 event Notified event "kernel.controller" to listener "Symfony\Component\HttpKernel\DataCollector\RequestDataCollector::onKernelController". 
{
    "event": "kernel.controller",
    "listener": "Symfony\\Component\\HttpKernel\\DataCollector\\RequestDataCollector::onKernelController"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\Security\Http\EventListener\IsGrantedAttributeListener::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\Security\\Http\\EventListener\\IsGrantedAttributeListener::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\HttpKernel\EventListener\CacheAttributeListener::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\CacheAttributeListener::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "ContainerNQG8xF6\RequestPayloadValueResolverGhost3590451::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "ContainerNQG8xF6\\RequestPayloadValueResolverGhost3590451::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\HttpKernel\EventListener\ErrorListener::onControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ErrorListener::onControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\Security\Http\Firewall\ContextListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\Security\\Http\\Firewall\\ContextListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\ResponseListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ResponseListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\WebLink\EventListener\AddLinkHeaderListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\WebLink\\EventListener\\AddLinkHeaderListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\DataCollector\RequestDataCollector::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\DataCollector\\RequestDataCollector::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\CacheAttributeListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\CacheAttributeListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\ProfilerListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ProfilerListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\ErrorListener::removeCspHeader". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ErrorListener::removeCspHeader"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\DisallowRobotsIndexingListener::onResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\DisallowRobotsIndexingListener::onResponse"
}
DEBUG 01:05:57 event Notified event "kernel.response" to listener "Symfony\Component\HttpKernel\EventListener\SessionListener::onKernelResponse". 
{
    "event": "kernel.response",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\SessionListener::onKernelResponse"
}
DEBUG 01:05:57 event Notified event "kernel.finish_request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleListener::onKernelFinishRequest". 
{
    "event": "kernel.finish_request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleListener::onKernelFinishRequest"
}
DEBUG 01:05:57 event Notified event "kernel.finish_request" to listener "Symfony\Component\HttpKernel\EventListener\RouterListener::onKernelFinishRequest". 
{
    "event": "kernel.finish_request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\RouterListener::onKernelFinishRequest"
}
DEBUG 01:05:57 event Notified event "kernel.finish_request" to listener "Symfony\Bundle\SecurityBundle\Debug\TraceableFirewallListener::onKernelFinishRequest". 
{
    "event": "kernel.finish_request",
    "listener": "Symfony\\Bundle\\SecurityBundle\\Debug\\TraceableFirewallListener::onKernelFinishRequest"
}
DEBUG 01:05:57 event Notified event "kernel.finish_request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleAwareListener::onKernelFinishRequest". 
{
    "event": "kernel.finish_request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleAwareListener::onKernelFinishRequest"
}
CRITICAL 01:05:57 request Uncaught PHP Exception ValueError: "unlink(): Argument #1 ($filename) must not contain any null bytes" at FileProfilerStorage.php line 351 
{
    "exception": {}
}
DEBUG 01:05:57 event Notified event "kernel.terminate" to listener "Symfony\Component\HttpKernel\EventListener\ProfilerListener::onKernelTerminate". 
{
    "event": "kernel.terminate",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ProfilerListener::onKernelTerminate"
}
CRITICAL 01:05:57 php Uncaught Error: unlink(): Argument #1 ($filename) must not contain any null bytes 
{
    "exception": {}
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\DebugHandlersListener::configure". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\DebugHandlersListener::configure"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\ValidateRequestListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ValidateRequestListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\SessionListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\SessionListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleListener::setDefaultLocale". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleListener::setDefaultLocale"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\RouterListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\RouterListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Component\HttpKernel\EventListener\LocaleAwareListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\LocaleAwareListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Bundle\SecurityBundle\Debug\TraceableFirewallListener::configureLogoutUrlGenerator". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Bundle\\SecurityBundle\\Debug\\TraceableFirewallListener::configureLogoutUrlGenerator"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Symfony\Bundle\SecurityBundle\Debug\TraceableFirewallListener::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Symfony\\Bundle\\SecurityBundle\\Debug\\TraceableFirewallListener::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.request" to listener "Knp\Bundle\PaginatorBundle\Subscriber\SlidingPaginationSubscriber::onKernelRequest". 
{
    "event": "kernel.request",
    "listener": "Knp\\Bundle\\PaginatorBundle\\Subscriber\\SlidingPaginationSubscriber::onKernelRequest"
}
DEBUG 01:05:57 event Notified event "kernel.controller" to listener "Symfony\Bundle\FrameworkBundle\DataCollector\RouterDataCollector::onKernelController". 
{
    "event": "kernel.controller",
    "listener": "Symfony\\Bundle\\FrameworkBundle\\DataCollector\\RouterDataCollector::onKernelController"
}
DEBUG 01:05:57 event Notified event "kernel.controller" to listener "Symfony\Component\HttpKernel\DataCollector\RequestDataCollector::onKernelController". 
{
    "event": "kernel.controller",
    "listener": "Symfony\\Component\\HttpKernel\\DataCollector\\RequestDataCollector::onKernelController"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\Security\Http\EventListener\IsGrantedAttributeListener::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\Security\\Http\\EventListener\\IsGrantedAttributeListener::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\HttpKernel\EventListener\CacheAttributeListener::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\CacheAttributeListener::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "ContainerNQG8xF6\RequestPayloadValueResolverGhost3590451::onKernelControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "ContainerNQG8xF6\\RequestPayloadValueResolverGhost3590451::onKernelControllerArguments"
}
DEBUG 01:05:57 event Notified event "kernel.controller_arguments" to listener "Symfony\Component\HttpKernel\EventListener\ErrorListener::onControllerArguments". 
{
    "event": "kernel.controller_arguments",
    "listener": "Symfony\\Component\\HttpKernel\\EventListener\\ErrorListener::onControllerArguments"
}

Stack Trace

ValueError 
ValueError:
unlink(): Argument #1 ($filename) must not contain any null bytes

  at vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:351
  at unlink()
     (vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:351)
  at Symfony\Component\HttpKernel\Profiler\FileProfilerStorage->removeExpiredProfiles()
     (vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:200)
  at Symfony\Component\HttpKernel\Profiler\FileProfilerStorage->write()
     (vendor/symfony/http-kernel/Profiler/Profiler.php:104)
  at Symfony\Component\HttpKernel\Profiler\Profiler->saveProfile()
     (vendor/symfony/http-kernel/EventListener/ProfilerListener.php:135)
  at Symfony\Component\HttpKernel\EventListener\ProfilerListener->onKernelTerminate()
     (vendor/symfony/event-dispatcher/Debug/WrappedListener.php:116)
  at Symfony\Component\EventDispatcher\Debug\WrappedListener->__invoke()
     (vendor/symfony/event-dispatcher/EventDispatcher.php:220)
  at Symfony\Component\EventDispatcher\EventDispatcher->callListeners()
     (vendor/symfony/event-dispatcher/EventDispatcher.php:56)
  at Symfony\Component\EventDispatcher\EventDispatcher->dispatch()
     (vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php:139)
  at Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher->dispatch()
     (vendor/symfony/http-kernel/HttpKernel.php:115)
  at Symfony\Component\HttpKernel\HttpKernel->terminate()
     (vendor/symfony/http-kernel/Kernel.php:157)
  at Symfony\Component\HttpKernel\Kernel->terminate()
     (vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php:53)
  at Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner->run()
     (vendor/autoload_runtime.php:29)
  at require_once('/var/www/schuellerlab.org/vendor/autoload_runtime.php')
     (public/index.php:5)
unlink(): Argument #1 ($filename) must not contain any null bytes (500 Internal Server Error)

Symfony Exception

Symfony Docs

ValueError

HTTP 500 Internal Server Error

unlink(): Argument #1 ($filename) must not contain any null bytes

Exception

ValueError

in /var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php (line 351)
  2.             if ($csvTime >= $minimalProfileTimestamp) {
  3.                 break;
  4.             }
  6.             @unlink($this->getFilename($csvToken));
  7.             $offset += \strlen($line);
  8.         }
  9.         fclose($handle);
  11.         file_put_contents($file.'.offset', $offset);
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php unlink (line 351)
  2.             if ($csvTime >= $minimalProfileTimestamp) {
  3.                 break;
  4.             }
  6.             @unlink($this->getFilename($csvToken));
  7.             $offset += \strlen($line);
  8.         }
  9.         fclose($handle);
  11.         file_put_contents($file.'.offset', $offset);
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php -> removeExpiredProfiles (line 200)
  1.                 $profile->getVirtualType() ?? 'request',
  2.             ]);
  3.             fclose($file);
  5.             if (1 === mt_rand(1, 10)) {
  6.                 $this->removeExpiredProfiles();
  7.             }
  8.         }
  10.         return true;
  11.     }
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/Profiler.php -> write (line 104)
  1.             if ($collector instanceof LateDataCollectorInterface) {
  2.                 $collector->lateCollect();
  3.             }
  4.         }
  6.         if (!($ret = $this->storage->write($profile)) && null !== $this->logger) {
  7.             $this->logger->warning('Unable to store the profiler information.', ['configured_storage' => $this->storage::class]);
  8.         }
  10.         return $ret;
  11.     }
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/EventListener/ProfilerListener.php -> saveProfile (line 135)
  1.             }
  2.         }
  4.         // save profiles
  5.         foreach ($this->profiles as $request) {
  6.             $this->profiler->saveProfile($this->profiles[$request]);
  7.         }
  9.         $this->profiles = new \SplObjectStorage();
  10.         $this->parents = new \SplObjectStorage();
  11.     }
in /var/www/schuellerlab.org/vendor/symfony/event-dispatcher/Debug/WrappedListener.php -> onKernelTerminate (line 116)
  1.         $this->priority ??= $dispatcher->getListenerPriority($eventName, $this->listener);
  3.         $e = $this->stopwatch->start($this->name, 'event_listener');
  5.         try {
  6.             ($this->optimizedListener ?? $this->listener)($event, $eventName, $dispatcher);
  7.         } finally {
  8.             if ($e->isStarted()) {
  9.                 $e->stop();
  10.             }
  11.         }
in /var/www/schuellerlab.org/vendor/symfony/event-dispatcher/EventDispatcher.php -> __invoke (line 220)
  2.         foreach ($listeners as $listener) {
  3.             if ($stoppable && $event->isPropagationStopped()) {
  4.                 break;
  5.             }
  6.             $listener($event, $eventName, $this);
  7.         }
  8.     }
  10.     /**
  11.      * Sorts the internal list of listeners for the given event by priority.
in /var/www/schuellerlab.org/vendor/symfony/event-dispatcher/EventDispatcher.php -> callListeners (line 56)
  1.         } else {
  2.             $listeners = $this->getListeners($eventName);
  3.         }
  5.         if ($listeners) {
  6.             $this->callListeners($listeners, $eventName, $event);
  7.         }
  9.         return $event;
  10.     }
in /var/www/schuellerlab.org/vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php -> dispatch (line 139)
  1.         try {
  2.             $this->beforeDispatch($eventName, $event);
  3.             try {
  4.                 $e = $this->stopwatch->start($eventName, 'section');
  5.                 try {
  6.                     $this->dispatcher->dispatch($event, $eventName);
  7.                 } finally {
  8.                     if ($e->isStarted()) {
  9.                         $e->stop();
  10.                     }
  11.                 }
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/HttpKernel.php -> dispatch (line 115)
  1.     /**
  2.      * @return void
  3.      */
  4.     public function terminate(Request $request, Response $response)
  5.     {
  6.         $this->dispatcher->dispatch(new TerminateEvent($this, $request, $response), KernelEvents::TERMINATE);
  7.     }
  9.     /**
  10.      * @internal
  11.      */
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/HttpKernel.php -> terminate (line 142)
  1.         }
  3.         $response->sendHeaders();
  4.         $response->sendContent();
  6.         $this->terminate($request, $response);
  7.     }
  9.     /**
  10.      * Handles a request to convert it to a response.
  11.      *
in /var/www/schuellerlab.org/vendor/symfony/http-kernel/EventListener/DebugHandlersListener.php -> terminateWithException (line 82)
  1.                         if ($hasRun) {
  2.                             throw $e;
  3.                         }
  5.                         $hasRun = true;
  6.                         $kernel->terminateWithException($e, $request);
  7.                     };
  8.                 }
  9.             } elseif ($event instanceof ConsoleEvent && $app = $event->getCommand()->getApplication()) {
  10.                 $output = $event->getOutput();
  11.                 if ($output instanceof ConsoleOutputInterface) {
in /var/www/schuellerlab.org/vendor/symfony/error-handler/ErrorHandler.php :: Symfony\Component\HttpKernel\EventListener\{closure} (line 535)
  1.             $this->exceptionHandler = null;
  2.         }
  4.         try {
  5.             if (null !== $exceptionHandler) {
  6.                 $exceptionHandler($exception);
  8.                 return;
  9.             }
  10.             $handlerException ??= $exception;
  11.         } catch (\Throwable $handlerException) {
ErrorHandler->handleException()

Stack Trace

ValueError 
ValueError:
unlink(): Argument #1 ($filename) must not contain any null bytes

  at /var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:351
  at unlink()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:351)
  at Symfony\Component\HttpKernel\Profiler\FileProfilerStorage->removeExpiredProfiles()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/FileProfilerStorage.php:200)
  at Symfony\Component\HttpKernel\Profiler\FileProfilerStorage->write()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/Profiler/Profiler.php:104)
  at Symfony\Component\HttpKernel\Profiler\Profiler->saveProfile()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/EventListener/ProfilerListener.php:135)
  at Symfony\Component\HttpKernel\EventListener\ProfilerListener->onKernelTerminate()
     (/var/www/schuellerlab.org/vendor/symfony/event-dispatcher/Debug/WrappedListener.php:116)
  at Symfony\Component\EventDispatcher\Debug\WrappedListener->__invoke()
     (/var/www/schuellerlab.org/vendor/symfony/event-dispatcher/EventDispatcher.php:220)
  at Symfony\Component\EventDispatcher\EventDispatcher->callListeners()
     (/var/www/schuellerlab.org/vendor/symfony/event-dispatcher/EventDispatcher.php:56)
  at Symfony\Component\EventDispatcher\EventDispatcher->dispatch()
     (/var/www/schuellerlab.org/vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php:139)
  at Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher->dispatch()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/HttpKernel.php:115)
  at Symfony\Component\HttpKernel\HttpKernel->terminate()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/HttpKernel.php:142)
  at Symfony\Component\HttpKernel\HttpKernel->terminateWithException()
     (/var/www/schuellerlab.org/vendor/symfony/http-kernel/EventListener/DebugHandlersListener.php:82)
  at Symfony\Component\HttpKernel\EventListener\DebugHandlersListener::Symfony\Component\HttpKernel\EventListener\{closure}()
     (/var/www/schuellerlab.org/vendor/symfony/error-handler/ErrorHandler.php:535)
  at Symfony\Component\ErrorHandler\ErrorHandler->handleException()